Sindroma Pre Eksitasi Asimtomatik: Ablasi Versus Konservatif


Wolff-Parkinson-White (WPW) is a sporadic and familial abnormality. Epidemiological
data indicate that 0.1% to 0.3% of the general population
have ECG findings suggesting that during sinus rhythm. The risk of sudden
cardiac death is around 0.25%. Patients with WPW syndrome is often
symptomatic because of cardiac arrhythmias. Sometimes the arrhythmia
can be life-threatening, and leads to sudden cardiac death. However, there
is still controversy in management of individuals with asymptomatic WPW
pattern. Despite radiofrequency catheter ablation remains the first line
therapy of the WPW syndrome, the risk of complications of this procedure
is almost the same as the risk of sudden cardiac death in asymptomatic
WPW. Therefore, an algorithm to determine the appropriate management
of asymptomatic WPW patients is needed.


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Helising G, Schneider M, Pustowoit A, Schmitt C. Accessory
Pathway. In: Schmitt C, Deisenhofer I, Zrenner B, eds. Catheter
ablation of cardiac arrhythmia : A practical approach. Munich:
Springer; 2006:77-102.

Timmermans C, Smeets JL, Rodriguez LM, Vrouchos G, van
den Dool A, Wellens HJ. Aborted sudden death in the Wolff-
Parkinson-White syndrome. Am J Cardiol 1995;76:492-4.

Klein GJ, Bashore TM, Sellers TD, Pritchett EL, Smith WM,
Gallagher JJ. Ventricular fibrillation in the Wolff-Parkinson-
White syndrome. N Engl J Med 1979;301:1080-5.

Cohen MI, Triedman JK, Cannon BC, et al. PACES/HRS
Expert Consensus Statement on the Management of the
Asymptomatic Young Patient with a Wolff-Parkinson-White
(WPW, Ventricular Preexcitation) Electrocardiographic
Pattern: Developed in partnership between the Pediatric
and Congenital Electrophysiology Society (PACES) and the
Heart Rhythm Society (HRS). Endorsed by the governing
bodies of PACES, HRS, the American College of Cardiology
Foundation (ACCF), the American Heart Association
(AHA), the American Academy of Pediatrics (AAP), and the
Canadian Heart Rhythm Society (CHRS). Heart Rhythm

Zipes DP, DiMarco JP, Gillette PC, et al. Guidelines for
clinical intracardiac electrophysiological and catheter ablation
procedures. A report of the American College of Cardiology/
American Heart Association Task Force on Practice Guidelines
(Committee on Clinical Intracardiac Electrophysiologic and
Catheter Ablation Procedures), developed in collaboration with
the North American Society of Pacing and Electrophysiology. J
Am Coll Cardiol 1995;26:555-73.

Issa Z, Miller J, Zipes D. Clinical arrhythmology and electrophysiology
: a companion to Braunwald’s heart disease. In: Issa
Z, ed. 1st edition ed. Philadelphia; 2009.

Obeyesekere MN, Leong-Sit P, Massel D, et al. Risk of arrhythmia
and sudden death in patients with asymptomatic preexcitation:
a meta-analysis. Circulation 2012;125:2308-15.

Pappone C, Santinelli V, Rosanio S, et al. Usefulness of invasive
electrophysiologic testing to stratify the risk of arrhythmic events
in asymptomatic patients with Wolff-Parkinson-White pattern:
results from a large prospective long-term follow-up study. J Am
Coll Cardiol 2003;41:239-44.

Teo WS, Klein GJ, Guiraudon GM, et al. Multiple accessory
pathways in the Wolff-Parkinson-White syndrome as a risk factor
for ventricular fibrillation. Am J Cardiol 1991;67:889-91.

Basso C, Corrado D, Rossi L, Thiene G. Ventricular preexcitation
in children and young adults: atrial myocarditis as a possible
trigger of sudden death. Circulation 2001;103:269-75.

Wellens HJ. Should catheter ablation be performed in asymptomatic
patients with Wolff-Parkinson-White syndrome?
When to perform catheter ablation in asymptomatic patients
with a Wolff-Parkinson-White electrocardiogram. Circulation
2005;112:2201-7; discussion 16.
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Sindroma Pre Eksitasi Asimtomatik: Ablasi Versus Konservatif. (2014). Indonesian Journal of Cardiology, 34(3), 188-96.
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