Perkembangan Implikasi Biologi dan Klinis Proprotein Convertase Subtilisin-Kexin 9

  • Djanggan Sargowo Departemen Kardiologi dan Kedokteran Vaskular Fakultas Kedokteran Universitas Brawijaya – RSUD dr. Saiful Anwar Malang

Abstract

Pada tahun 2003 Proprotein Convertase Subtilisin-Kexin 9 (PCSK9) berhasil diidentifikasi.1 PCSK9 berfungsi meningkatkan kadar LDL Cholesterol (LDL-C) melalui degradasi LDL Receptor (LDLR).2 Penemuan PCSK9 telah merevolusi serta merupakan perkembangan terpenting pada bidang riset kardiovaskular satu dekade terakhir, terutama dalam regulasi LDL-C. 1

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References

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Published
2017-04-18

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How to Cite
Sargowo, D. (2017). Perkembangan Implikasi Biologi dan Klinis Proprotein Convertase Subtilisin-Kexin 9. Indonesian Journal of Cardiology, 37(3), 117-121. https://doi.org/10.30701/ijc.v37i3.574