Applicability of Distal Radial Artery Access in Acute Coronary Syndrome: A Single-Center Observational Registry Study
DOI:
https://doi.org/10.30701/ijc.2112Keywords:
acute coronary syndrome, angiography, cardiac catheterization, distal radial access, percutaneous coronary interventionAbstract
Background: Distal Radial Artery Access (DRA) has emerged as an alternative vascular access for Coronary Angiography (CGA) and Percutaneous Coronary Intervention (PCI). However, real-world data regarding its procedural feasibility and outcomes remain limited. This study aimed to evaluate the feasibility and procedural outcomes of distal radial artery access in patients undergoing CGA and/or PCI.
Methods: We conducted a single-center observational registry including consecutive patients undergoing CGA or PCI with an initial attempt at DRA access. The primary feasibility endpoint was successful completion of the procedure via DRA without crossover to an alternative vascular access site.
Results: A total of 835 patients were included in the analysis, representing an all-comer cohort including both Acute Coronary Syndrome (ACS) and Chronic Coronary Syndrome (CCS) presentations. The clinical indications included Non-ST-segment Elevation Myocardial Infarction (NSTEMI) in 326 patients (39%), Unstable Angina Pectoris (UAP) in 292 patients (35%), ST-segment Elevation Myocardial Infarction (STEMI) in 167 patients (20%), and stable coronary artery disease in 50 patients (6%). The primary feasibility endpoint, successful completion of the procedure via DRA without crossover, was achieved in 811 patients (97.1%). Crossover to an alternative access site occurred in 24 patients (2.9%), including contralateral proximal radial access in 13 patients (54.2%), femoral access in 10 patients (41.7%), and ipsilateral proximal radial access in 1 patient (4.2%).
Conclusions: DRA access demonstrated high procedural feasibility for CGA and PCI in a real-world cohort including both acute and CCS presentations.
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1. Al-Azizi KM, Grewal V, Gobeil K, Maqsood K, Haider A, Mohani A, Giugliano G, Lotfi AS. The left distal transradial artery access for coronary angiography and intervention: a US experience. Cardiovasc Revasc Med. 2019;20(9):786–9.
2. Ferrante G, Rao SV, Jüni P, Da Costa BR, Reimers B, Condorelli G, Anzuini A, Jolly SS, Bertrand OF, Krucoff MW, Windecker S, Valgimigli M. Radial versus femoral access for coronary interventions across the entire spectrum of patients with coronary artery disease: a meta-analysis of randomized trials. JACC Cardiovasc Interv. 2016;9(14):1419–34.
3. Aoun J, Hattar L, Dgayli K, Wong G, Bhat T. Update on complications and their management during transradial cardiac catheterization. Expert Rev Cardiovasc Ther. 2019;17(10):741–51.
4. Kaledin A, Kochanov I, Podmetin PS, Seletsky SS, Ardeev VN. Distal radial artery in endovascular interventions. 2017. https://www.researchgate.net/publication/319162208_Distal_radial_artery_in_endovascular_interventions. Accessed 15 Nov 2025
5. Babunashvili A, Dundua D. Recanalization and reuse of early occluded radial artery within 6 days after previous transradial diagnostic procedure. Catheter Cardiovasc Interv. 2011;77:530–6.
6. Regueiro A, Freixa X, Bartolomé Y, Postigo C, Sales S, Falco J. Successful percutaneous treatment of an arteriovenous fistula after radial primary percutaneous coronary intervention. Cardiovasc Interv. 2014;7(9)–4.
7. Costa F, van Leeuwen MA, Daemen J, Diletti R, Kauer F, van Geuns RJ, Lighart J, Witberg K, Zijlstra F, Valgimigli M, Van Mieghem NM. The Rotterdam radial access research: ultrasound-based radial artery evaluation for diagnostic and therapeutic coronary procedures. Circ Cardiovasc Interv. 2016;9(6).
8. Lee JW, Kim CJ, Lee BK, Ahn SG, Youn SJ, Lee JH, Jeon HS, Kim SY, Jang J, Bu S, Ahn HS, Lim S, Yim HW, Lee SH. Distal Radial Access vs Transradial Access in Patients With ST-Segment Elevation Myocardial Infarction: The DRAMI Trial. JACC Adv. 2025;4(11 Pt 1):102200.
9. Lubis L, Yahya AF, Melina AL, Wirata G, Lesmana R, Dewi GT, Purba A. The success rate of distal transradial access on invasive cardiology procedures: the first Indonesian experience. Bali Med J. 2021;10(1):486-490
10. Adwiarto SK, Windityasari ND, Wibowo RH, Dewi AU. Distal Radial Access for Angiography and Intervention. In: Abstracts: Original Research Abstract [internet]. 13th Indonesian Society of Interventional Cardiology (ISICAM): Supplement Overview. Indonesian J Cardiol. 2021;42(Suppl_B):1-2. Available from: https://doi.org/ 10.30701/ijc.1237
11. Kiemeneij F. Left distal transradial access in the anatomical snuffbox for coronary angiography (ldTRA) and interventions (ldTRI). EuroIntervention. 2017;13(7):851–857.
12. Sgueglia GA, Lee BK, Cho BR, Babunashvili A, Lee JB, Lee JW, Lee JW, Schenke K, Lee SY, Harb S. Distal radial access: consensus report of the first Korea-Europe Transradial Intervention meeting. J Am Coll Cardiol Intv. 2021;14(8):892–906.
13. Cai G, Huang H, Li F, Shi G, Yu X, Yu L. Distal transradial access: a review of the feasibility and safety in cardiovascular angiography and intervention. BMC Cardiovasc Disord. 2020;20:356.
14. Koutouzis M, Kontopodis E, Tassopoulos A, Tsiafoutis I, Katsanou K, Rigatou A, Didagelos M, Andreou K, Lazaris E, Oikonomidis N, Maniotis C, Ziakas A. Distal versus traditional radial approach for coronary angiography. Cardiovasc Revasc Med. 2019;20(8):678–80.
15. Gasparini GL, Garbo R, Gagnor A, Oreglia J, Mazzarotto P. First prospective multicentre experience with left distal transradial approach for coronary chronic total occlusion interventions using a 7 Fr Glidesheath slender. EuroIntervention. 2019;15(1):126–8.
16. Flores EA. Making the right move: use of the distal radial artery access in the hand for coronary angiography and percutaneous coronary interventions. Cath Lab Digest. 2018;26(12):16–25.
17. Aoi S, Htun WW, Freeo S, Lee S, Kyaw H, Alfaro V, Coppola J, Pancholy S, Kwan T. Distal transradial artery access in the anatomical snuffbox for coronary angiography as an alternative access site for faster hemostasis. Catheter Cardiovasc Interv. 2019;94(5):651–7.
18. Kim Y, Ahn Y, Kim I, Lee DH, Kim MC, Sim DS, Hong YJ, Kim JH, Jeong MH. Feasibility of coronary angiography and percutaneous coronary intervention via left snuffbox approach. Korean Circ J. 2018;48(12):1120–30.
19. Lee JW, Park SW, Son JW, Ahn SG, Lee SH. Real-world experience of the left distal transradial approach for coronary angiography and percutaneous coronary intervention: a prospective observational study (LeDRA). EuroIntervention. 2018;14(9)–e1003.
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