Torsades de Pointes pada pasien Hipokalemia: Peranan Afterdepolarization pada mekanisme Takiaritmia
Abstract
KasusSeorang wanita usia 56 tahun, dengan riwayat gagaljantung dalam pengobatan dengan obat diuretik furosemid, mengalami muntaber selama 3 hari terakhir. Saat tiba di UGD, EKG dengan irama sinus tiba-tiba mengalami degenerasi menjadi takikardia QRS lebar polimorfik saat perekaman. Presentasi hemodinamik pasien menjadi tidak stabil sehingga diputuskan untuk dilakukan kardioversi elektrik. Setelah defibrilasi, irama jantung kembali menjadi irama sinus dan hasil laboratorium menujukkan hipokalemia berat (2,4 meq/L). Setelah koreksi potassium dan perawatan, pasien membaik kemudian dipulangkan. Apa mekanisme tercetusnya torsades de pointes pada pasien ini?
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References
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Electrocardiographic manifestations: electrolyte abnormalities.
J Emerg Med 2004;27(2):153-60.
El-Sherif N, Turitto G. Electrolyte disorders and arrythmogenesis.
Cardiol J 2011;18(3):233-
Glancy DL, Wiklow FE, Rochon BJ. Electrocardiogram after 2
weeks of diarrhea. Proc (Bayl Univ Med Cent) 2010;23(2):173-
4.
Pérez Riera AR, Ferreira C, Filho CF, et al. The enigmatic
sixth wave of the electrocardiogram: the U wave. Cardiol
J 2008;15 (5): 408–21.
Natale A, Wazni O, eds. Handbook of Cardiac Electrophysiology.
1st Ed. London:Informa Healhcare; 2007.
Issa ZF, Miller JM, Zipes DP, eds.Clinical Arrhytmology
and Electrophysiology : Companion to Braunwald’s Heart
Disease.2nd Ed. Philadelphia : Elsevier; 2012
Osadchii OE. Mechanisms of hypokalemia-induced ventricular
arrhytmogenicity. Fundam Clin Pharmacol. 2010
Oct;24(5):547-59
Published
2014-03-25
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How to Cite
Tondas, A., & Yuniadi, Y. (2014). Torsades de Pointes pada pasien Hipokalemia: Peranan Afterdepolarization pada mekanisme Takiaritmia. Indonesian Journal of Cardiology, 34(3), 204-6. https://doi.org/10.30701/ijc.v34i3.344
Section
Forum Aritmia
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