Balloon Mitral Valvulotomy (BMV): Mengapa Resistensi Paru Tidak Selalu Menurun?
Abstract
Mitral stenosis merupakan kelainan yang di negara kita masih merupakan masalah, terutama mengakibatkan menurunnya kemampuan fisik seseorang sehingga mengurangi kualitas hidup yang diinginkan. Hal ini disebabkan masih prevalennya demam rematik akutpada anak-anak yang tidak diobati dengan memadai dengan sekuele utamanya mengenai katup mitral.Salah satu akibat dari mitral stenosis adalah meningkatnya tekanan pada sirkulasi paru akibat bendungan pada system vena paru dan menimbulkan hipertensi pulmonal. Meskipun upaya untuk menghilangkan penyempitan katup baik dengan intervensi bedah maupun non bedah dengan Balloon Mitral Valvuloplasty (“BMV”) mendapatkan hasil yang baik dengan menghilangkan penyempitan pada aliran paru, namun tidak semua penderita yang menjalani upaya ini dapat kembali normal dari segi morbiditas karena fisiologi yang normal tidak semuanya dapat kembali berjalan terutama pada penderita-penderita lanjut yang terlalu lama mengalami abnormalitas dari fisiologi aliran paru.
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References
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Tanabe Y, Suzuki M, Takahashi M, Oshima M, Yamazaki Y, Yamaguchi T, Igarashi Y, Tamura Y, Yamazoe M, Shibata A. Acute effect of percutaneous transvenous mitral commissurotomy on ventilator and hempdynamic responses to exercise. Pathophysiologic basis for early symptomatic improvement. Circulation 1993;88:1770-1778.
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Levine MJ, Weinstein JS, Diver DJ, Berman AD, Wyman RM, Cunningham MJ, Safian RD, Grossman W, McKay RG. Progressive Improvement in Pulmonary Vascular Resistance After Perdcutaneous Mitral Valvuloplasty. Circulation 1989;79:1061-1067.
McCredie R M.The Pulmonary Capillary Bed in Various Forms of Pulmonary Hypertension.Circulation .1966;33:854-861.
Nashikimi T, Nagata S, Sasaki T, Yoshihara Y, Nagaya N, Horio T, Matsuo H, Matsuoka H, Kangawa K. The active molecular form of plasma adrenomodulin is extracted in the pulmonary circulation in patients with mitral stenosis:possible role of adrenomodulin in pulmonary hypertension. Clin Science. 2001;100:61-66.
Yamamoto K, Ikeda U, Mito H, Fujikawa H, Sekiguchi H, Shimada K. Endothelin production in pulmonary circulation of patients with mitral stenosis. Circulation. 1994;89:2093-2098.
Tanabe Y, Suzuki M, Takahashi M, Oshima M, Yamazaki Y, Yamaguchi T, Igarashi Y, Tamura Y, Yamazoe M, Shibata A. Acute effect of percutaneous transvenous mitral commissurotomy on ventilator and hempdynamic responses to exercise. Pathophysiologic basis for early symptomatic improvement. Circulation 1993;88:1770-1778.
Purnawarman A, Haryono N, Sakidjan I. Faktor-faktor yang mempengaruhi perubahan resistensi vaskular pulmonal segera pasca komisurotomi mitral transvena perkutan pada stenosis mitral. J Kardiol Indones. 2011; 32:169-77
Levine MJ, Weinstein JS, Diver DJ, Berman AD, Wyman RM, Cunningham MJ, Safian RD, Grossman W, McKay RG. Progressive Improvement in Pulmonary Vascular Resistance After Perdcutaneous Mitral Valvuloplasty. Circulation 1989;79:1061-1067.
McCredie R M.The Pulmonary Capillary Bed in Various Forms of Pulmonary Hypertension.Circulation .1966;33:854-861.
Nashikimi T, Nagata S, Sasaki T, Yoshihara Y, Nagaya N, Horio T, Matsuo H, Matsuoka H, Kangawa K. The active molecular form of plasma adrenomodulin is extracted in the pulmonary circulation in patients with mitral stenosis:possible role of adrenomodulin in pulmonary hypertension. Clin Science. 2001;100:61-66.
Yamamoto K, Ikeda U, Mito H, Fujikawa H, Sekiguchi H, Shimada K. Endothelin production in pulmonary circulation of patients with mitral stenosis. Circulation. 1994;89:2093-2098.
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How to Cite
Rachman, O. (1). Balloon Mitral Valvulotomy (BMV): Mengapa Resistensi Paru Tidak Selalu Menurun?. Indonesian Journal of Cardiology, 32(3), 179-80. https://doi.org/10.30701/ijc.v32i3.95
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