Contrast Induced Nephropathy

Abstract

Incidens of contrast induced nephropathy (CIN) ranging from 0 to 100% in retrospective cohort studies depend on its definition, method of investigation and subject characterization. In National Cardiovasculars Center Harapan Kita, CIN incidence after percutaneous coronary intervention was 25% using definition of 0.5 mg/dl increase of serum creatinine. Clinical spectrum of CIN is widely variably from only creatinine serum increment to acute renal failure.
Pathogenesis of CIN is related to hemodynamic compromize of renal blood flow and direct toxic effect of contrast media. Some factors were identified as CIN risk factors such as previous renal status, diabetes mellitus, hidration status, contrast volume and osmality. Score system has been developed to predict CIN risk after percutaneous coronary intervention. The Society of Cardiovascular Angiography and Intervention (SCAI) proposed guideline to prevent CIN after percutaneous coronary interventions.

Downloads

Download data is not yet available.

References

Tublin ME, Murphy ME, Tessler FN. Current concepts in contrast media-induced nephropathy. Am J Radiol.1998; 171:933-9.

Bettmann MA. Contrast medium-Induced Nephropathy : critical review of the existing clinical evidence. Nephrol Dial Transplant. 2005; 20 (suppl 1): i12-7.

Berns J, Rudnick M. Radiocontrast media associated nephrotoxicity. Kidney. 1992; 24: 1-5.

Deray G. Nephrotoxicity of contrast media. Nephrol Dial Transplant. 1999; 14: 2602-6.

Parfrey PS, Griffiths SM, Barrett BJ, dkk. Contrast material-induced renal failure in patients with diabetes mellitus, renal insufficiency, or both. N Engl J Med.1989; 320:143-53.

Bakris Gl, Lass N, Gaber AO, dkk. Radiocontrast medium induced declines in renal function: a role for oxygen free radicals. Am J Physiol. 1990; 258: F115-20.

Asad PV, Priatna A, Spokes K, Epstein FH. Changes in intra-renal oxygenation as evaluated by BOLD MRI in a rat kidney model for radiocontrast nephropathy. J Magn Reson Imaging. 000; 13: 744-7.

Hayman LA, Migliore PJ. Contrast-induced renal failure. Radiology.1980; 137: 867-9.

Katzberg RW. Urography into the 21st century: new contrast media, renal handling, imaging characteristics, and nephrotoxicity. Radiology. 1997; 204: 297–312.

Davidson CJ, Hlatky M, Morris KG, dkk. Cardiovascular and renal toxicity of a nonionic radiographic contrast agent after cardiac catheterization: a prospective trial. Ann Intern Med. 1989; 110: 119-24.

Aspelin P, Aubry P, Franssen SG. Nephrotoxic effects in high risk patients undergoing angiography. N Eng J Med. 2003; 6: 491-9.

Alwall N, Erlanson P, Tornberg A. Clinical course of renal failure occurring after intravenous urography. N Eng J Med. 1955; 268: 1236-7.

Gleeson TG, Bulugahapitiya S. Contrast induced nephropathy. Am J Roentgenol. 2004; 183: 1673-9.

Kolonko A, Kokot F, Wiecek A. Contrast –associated nephropathy-old clinical problem and new therapeutic perspectives. Nephrol Dial Transplant. 1998; 13: 803-6.

Marenzi G, Assanelli E, Marana I, dkk. N-acetylcysteine and contrast-induced nephropathy in primary angioplasty. N Eng J Med. 2006; 354: 2773-82.

Zirogiannis P, Rentoukas E, Lazaros G. Contrast Media Induced Nephropathy in Patients Undergoing Catheterisation. Hellenic J Cardiol. 2004; 45:107-13.

Yuniadi Y, Ningrum NR. Risk factors and incidence of contrast induced nephropathy following coronary intervention. Med J Indones. 2008; 17: 131-6.

Rudnick M, Berns J, Cohen R, Goldfarb S. Nephrotoxic risks of renal angiography: contrast media-associated nephrotoxicity and atheroembolism—a critical review. Am J Kidney Dis. 1994; 24: 713-27.

Rich MW, Crecelius CA. Incidence, risk factors, and clinical course of acute renal insufficiency after cardiac catheterization in patients 70 years of age or older: a prospective study. Arch Intern Med. 1990; 150: 1237-42.

Love L, Johnson M, Bresler M, dkk. The persistent computed tomography nephrogram: its significance in the diagnosis of contrast-associated nephropathy. Br J Radiol. 1994; 67: 951-7.

Levy EM, Viscoli CM, Horwitz RI. The effect of acute renal failure on mortality: a cohort analysis. JAMA. 1996; 275: 1489-94.

Goldenberg I, Matetzky S. Nephropathy induced by contrast media: pathogenesis, risk factors and preventive strategies. CMAJ. 2005; 172: 1461-71.

Lautin EM, Freeman NJ, Schoenfeld AH, dkk. Radiocontrast-associated renal dysfunction: a comparison of lower-osmolality and conventional high-osmolality contrast media. Am J Radiol. 1991; 157: 59-65.

Mueller C, Seidensticker P, Buettner H, Perruchoud A, Staub D, Christ A. Incidence of contrast nephropathy in patients receiving comprehensive intravenous and oral volume supplementation. Swiss med wkly. 2005; 135: 286-90.

Cigarroa RG, Lange RA, Williams RH, Hillis LD. Dosing of contrast material to prevent contrast nephropathy in patients with renal disease. Am J Med. 1989; 86: 649-52.

Chalmers N, Jackson RW. Comparison of iodixanol and iohexol in renal impairment. Br J Radiol. 1999; 72: 701-3.

Mehran R, Aymong ED, Nikolsky E, Lasic Z, Iakovou I, Fahy M, dkk. A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation. J Am Coll Cardiol. 2004; 44: 1393-9.

Schweiger MJ, Chambers CE, Davidson CJ, dkk. Prevention of contrast induced nephropathy: Recommendations for the high risk patient undergoing Cardiovascular Procedures. Cath Cardiovasc Interven. 2007; 69:135–40.
Views & Downloads
Abstract views: 56   
PDF (Bahasa Indonesia) downloads: 3   
How to Cite
Contrast Induced Nephropathy. (1). Indonesian Journal of Cardiology, 30(2), 71-9. https://doi.org/10.30701/ijc.v30i2.166
Section
Review Article