Penyakit Jantung Pada Perempuan
Abstract
Penyakit kardiovaskular diklaim sebagai penyebab kematian nomor satu bagi perempuan diatas usia 65 tahun di benua Europa, masalah ini dikemukakan secara lengkap oleh Angela H.E.M. Maas, MD, PhD dan Harry Suryapranata, MD, PhD dari Isala Klinieken, Zwolle -The Netherlands, dalam jurnal edisi ketiga ini. Menurut survai di negeri kincir angin itu, perempuan kurangmemahami ancaman penyakit kardiovaskular, umumnya mereka lebih jarang menjalani uji latih jantung, apalagi angiografi diagnostik dan intervensi.
Hormon estrogen berperan melindungi perempuan dari PJK, oleh karenanya infark miokard akut terjadi pada usia yang lebih tua dibanding laki-laki. Mereka juga mempunyai risiko kematian lebih tinggi dan komorbiditas faktor risiko penyakit jantung koroner (PJK) yang lebih besar. Estrogen berperan dalam pengaturan faktor metabolisme, seperti lipid, petanda inflamasi, sistim trombotik, vasodilatasi reseptor adan ß. Oleh karena itu, terjadinya menopause berpengaruh terhadap kejadian PJK.
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References
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Vaccarino V, Parsons L, Every NR, Barron HV, Krumholz HM. Sex-based differences in early mortality after myocardial infarction. National Registry of Myocardial Infarction 2 Participants. N Engl J Med 1999; 341: 217-225.
Ossewaarde ME, Bots ML, Verbeek AL et al. Age at menopause, cause-specific mortality and total life expectancy. Epidemiology 2005;16:556-62.
Bairey Merz CN, Johnson BD, Sharaf BL et al. Hypoestro-genemia of hypothalamic origin and coronary artery disease in premenopausal women: a report from the NHLBI-sponsored WISE study. J Am Coll Cardiol 2003;41: 413-419.
Huxley R, Barzi F, Woodward M. Excess risk of fatal coronary heart disease associated with diabetes in men and women: meta-analysis of 37 prospective cohort studies. BMJ 2006;332:73-78.
Vaccarino V, Parsons L, Every NR, Barron HV, Krumholz HM. Sex-based differences in early mortality after myocardial infarction. National Registry of Myocardial Infarction 2 Participants. N Engl J Med 1999; 341: 217-225.
Ossewaarde ME, Bots ML, Verbeek AL et al. Age at menopause, cause-specific mortality and total life expectancy. Epidemiology 2005;16:556-62.
Bairey Merz CN, Johnson BD, Sharaf BL et al. Hypoestro-genemia of hypothalamic origin and coronary artery disease in premenopausal women: a report from the NHLBI-sponsored WISE study. J Am Coll Cardiol 2003;41: 413-419.
Huxley R, Barzi F, Woodward M. Excess risk of fatal coronary heart disease associated with diabetes in men and women: meta-analysis of 37 prospective cohort studies. BMJ 2006;332:73-78.
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How to Cite
Rahajoe, A. (1). Penyakit Jantung Pada Perempuan. Indonesian Journal of Cardiology, 28(3), 169-170. https://doi.org/10.30701/ijc.v28i3.237
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