Cardiac Resynchronization Therapy: Kapan dapat kita lakukan?
Abstract
Gagal jantung (GJ) merupakan penyebab utama perawatan pasien di rumah sakit Amerika Serikat, dan merupakan kasus yang memakan biaya terbanyak per tahunnya. Sekitar 500.000 kasus baru ditemukan setiap tahun, dan tak kurang dari 5 juta orang kini di Amerika menderita GJ.Studi mengenai terapi neurohormonal telah mencapai puncaknya, tambahan terapi selain penghambat renin-angiotensin-aldosteron dan adrenergik, belum terbukti memberi tambahan manfaat yang signifikan. Sementara itu, laporan studi mengenai device therapy(pacemakers, implantable
defibrillators, danventricular assist devices)pada GJ
banyak yang memberi hasil positif.
Khusus mengenai cardiac resynchronization therapy(CRT), telah banyak studi yang melaporkan manfaatnya pada GJ, dan telah pula dimasukkan dalam guideline Heart Failure sebagai salah satu terapi GJ. Meski demikian hasil pemasangan CRT masih ber variasi, dan membawa risiko komplikasi. Oleh karenanya, pemasangan CRT memerlukan kriteria seleksi pasien yang ketat dan tepat, sehingga rasio keuntungan-risiko dapat optimal.
Laporan kasus ini menguraikan tentang sebuah kasus pemasangan CRT. Akan dibahas mengenai kapan sebaiknya pemasangan CRT dilakukan, tatalaksana GJ, prediksi adanya disinkroni ventrikel, dan prognosis CRT berdasarkan elektrokardiogram (EKG) dan ekokardiogram.
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References
Aronow WS. Epidemiology, Pathophysiology, Prognosis, and Treatment of Systolic and Diastolic Heart Failure. Cardiology in Review 2006; 14:108–24
Scow DT, Smith ED Shaughnessy AF, Combination Therapy with ACE Inhibitors and Angiotensin-Receptor Blockers in Heart Failure. Am Fam Physician 2003; 68:1795-8
Mehra MR, Greenberg BH. Cardiac resynchronization therapy: caveat medicus! J. Am. Coll. Cardiol. 2004; 43;1145-8
Jeffery ME, Jessup M. The epidemiology of heart failure. In: Man Yu C, Hayes DL, Auricchio A. Cardiac resynchronization therapy. Massachusetts: Blackwell; 2006. p. 8-10
Haas GJ, Abraham W. Comprehensive pharmacologic management strategies for heart failure. In: Man Yu C, Hayes DL, Auricchio A. Cardiac resynchronization therapy. Massachusetts: Blackwell; 2006.
Auricchio A, Stellbrink C, Butter C, et al. Pacing therapies in congestive heart failure II study group; Guidant Heart Failure Research Group. Clinical efficacy of cardiac resynchronization therapy using left ventricular pacing in heart failure patients stratified by severity of ventricular conduction delay. J Am Coll Cardiol 2003;42:2109-16
Cazeau S, Leclercq C, Lvergne T, et al. Multisite Stimulation in Cardiomyopathies (MUSTIC) Study Investigators. Effect of multisite biventricular pacing in patients with heart failure and intraventricular conduction delay. N Wngl J Med 2001;344:873-80
Abraham W, Fisher W, Smith A, Delurgio DB, Leon AR, Loh E, et al. Cardiac resynchronization therapy in chronic heart failure. N Engl J Med. 2002;346:1845-53
Bradley DJ, Bradley EA, Baughman KL, Berger RD, Calkins H, Goodman S. Cardiac resynchronization and death from progressive heart failure: a meta-analysis of randomized controlled trials. JAMA 2003;289:730-40
Bristow MR, Saxon LA, Boehmer J, et al. Comparison of Medical Therapy, Pacing and Defibrillation in Heart Failure (COMPANION) Investigators. Cardiac resynchronization therapy with or without an imnplantable defibrillator in advanced chronic heart failure. N Engl J Med 2004; 350:2140-50
Hunt S, Abraham W, Chin M, , Feldman A, Francis G, Ganiats T, et al. ACC/AHA 2005 Guideline update for the diagnosis and management of chronic heart failure in the adult. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure).
Swedberg K, Cleland J, Dargie H, Drexler H, Follath F, Komajda M. Guidelines for the diagnosis and treatment for chronic heart failure (update 2005). The task force for the diagnosis and treatment for chronic heart failure of European Society of Cardiology
Lane RE, Chow AWC, Chin D, Mayet J. Selection and optimisation of biventricular pacing: the role of echocardiography. Heart 2004;90;10-16
Pitzalis M, Iacoviello M, Romito R, Massari F, Rizzon B, Luzzi G. Cardiac resynchronization therapy tailored by echocardiographic evaluation of ventricul ar asynchrony. J Am Coll Cardiol 2002;40:1615–22
Aronow WS. Epidemiology, pathophysiology, prognosis, and treatment of systolic and diastolic heart failure. Cardiology in Review 2006;14: 108–24
Sogaard P, Egeblad H, Pedersen AK, et al. Sequential versus simultaneous biventricular resynchronization for severe heart failure: evaluation by tissue Doppler imaging. Circulation 2002;106:2078–84
Kiès P, Bax JJ, Molhoek SG, Bleeker GB, Zeppenfeld K, Bootsma M, et al.Effect of cardiac resynchronization therapy on inducibility of ventricular tachyarrhythmias in cardiac arrest survivors with either ischemic or idiopathic dilated cardiomyopathy. Am J Cardiol 2005;95:1111–4.
Scow DT, Smith ED Shaughnessy AF, Combination Therapy with ACE Inhibitors and Angiotensin-Receptor Blockers in Heart Failure. Am Fam Physician 2003; 68:1795-8
Mehra MR, Greenberg BH. Cardiac resynchronization therapy: caveat medicus! J. Am. Coll. Cardiol. 2004; 43;1145-8
Jeffery ME, Jessup M. The epidemiology of heart failure. In: Man Yu C, Hayes DL, Auricchio A. Cardiac resynchronization therapy. Massachusetts: Blackwell; 2006. p. 8-10
Haas GJ, Abraham W. Comprehensive pharmacologic management strategies for heart failure. In: Man Yu C, Hayes DL, Auricchio A. Cardiac resynchronization therapy. Massachusetts: Blackwell; 2006.
Auricchio A, Stellbrink C, Butter C, et al. Pacing therapies in congestive heart failure II study group; Guidant Heart Failure Research Group. Clinical efficacy of cardiac resynchronization therapy using left ventricular pacing in heart failure patients stratified by severity of ventricular conduction delay. J Am Coll Cardiol 2003;42:2109-16
Cazeau S, Leclercq C, Lvergne T, et al. Multisite Stimulation in Cardiomyopathies (MUSTIC) Study Investigators. Effect of multisite biventricular pacing in patients with heart failure and intraventricular conduction delay. N Wngl J Med 2001;344:873-80
Abraham W, Fisher W, Smith A, Delurgio DB, Leon AR, Loh E, et al. Cardiac resynchronization therapy in chronic heart failure. N Engl J Med. 2002;346:1845-53
Bradley DJ, Bradley EA, Baughman KL, Berger RD, Calkins H, Goodman S. Cardiac resynchronization and death from progressive heart failure: a meta-analysis of randomized controlled trials. JAMA 2003;289:730-40
Bristow MR, Saxon LA, Boehmer J, et al. Comparison of Medical Therapy, Pacing and Defibrillation in Heart Failure (COMPANION) Investigators. Cardiac resynchronization therapy with or without an imnplantable defibrillator in advanced chronic heart failure. N Engl J Med 2004; 350:2140-50
Hunt S, Abraham W, Chin M, , Feldman A, Francis G, Ganiats T, et al. ACC/AHA 2005 Guideline update for the diagnosis and management of chronic heart failure in the adult. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure).
Swedberg K, Cleland J, Dargie H, Drexler H, Follath F, Komajda M. Guidelines for the diagnosis and treatment for chronic heart failure (update 2005). The task force for the diagnosis and treatment for chronic heart failure of European Society of Cardiology
Lane RE, Chow AWC, Chin D, Mayet J. Selection and optimisation of biventricular pacing: the role of echocardiography. Heart 2004;90;10-16
Pitzalis M, Iacoviello M, Romito R, Massari F, Rizzon B, Luzzi G. Cardiac resynchronization therapy tailored by echocardiographic evaluation of ventricul ar asynchrony. J Am Coll Cardiol 2002;40:1615–22
Aronow WS. Epidemiology, pathophysiology, prognosis, and treatment of systolic and diastolic heart failure. Cardiology in Review 2006;14: 108–24
Sogaard P, Egeblad H, Pedersen AK, et al. Sequential versus simultaneous biventricular resynchronization for severe heart failure: evaluation by tissue Doppler imaging. Circulation 2002;106:2078–84
Kiès P, Bax JJ, Molhoek SG, Bleeker GB, Zeppenfeld K, Bootsma M, et al.Effect of cardiac resynchronization therapy on inducibility of ventricular tachyarrhythmias in cardiac arrest survivors with either ischemic or idiopathic dilated cardiomyopathy. Am J Cardiol 2005;95:1111–4.
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How to Cite
Priyana, A. (1). Cardiac Resynchronization Therapy: Kapan dapat kita lakukan?. Indonesian Journal of Cardiology, 28(3), 215-219. https://doi.org/10.30701/ijc.v28i3.244
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