Biomarker pada Infark Miokard Akut: Diperlukan yang lebih Dini

  • Suko Adiarto Departemen Kardiologi dan Kedokteran Vaskular FKUI dan Pusat Jantung Nasional Harapan Kita, jln S Parman Kav 87 Jakarta 11420
DOI: https://doi.org/10.30701/ijc.v32i4.81

Abstract

Paling tidak dalam 4 dekade terakhir, Infark Miokard Akut (IMA) masih menempati urutan pertama dalam daftar penyakit penyebab kematian di seluruh dunia. Secara historis, terdapat kemajuan yang sangat pesat dalam penatalaksanaan penyakit ini, baik dalam segi diagnostik, terapi medikamentosa, maupun tindakan revaskularisasi. Khususnya di bidang diagnostik, penggunaan 3 kriteria WHO yang meliputi nyeri dada tipikal, perubahan EKG dan meningkatnya biomarker (enzim) yang spesifik sangat membantu meningkatkan akurasi diagnostik IMA secara signifikan. Bandingkan, pada tahun 1940­1950 hanya sekitar 15 persen penderita yang dirawat di ICCU dengan dugaan ternyata benar­benar mengalami IMA.
Kemajuan di bidang diagnostik juga diikuti oleh kemajuan yang sangat pesat dalam penata laksanaan IMA, dimana fokus utama tatalaksana IMA telah bergeser dari limitasi luasnya infark dengan cara menurunkan kebutuhan oksigen miokard menjadi terapi reperfusi, baik dengan cara farmakologi (fibrinolitik) maupun secara mekanik (Primary PCI)

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How to Cite
Adiarto, S. (1). Biomarker pada Infark Miokard Akut: Diperlukan yang lebih Dini. Indonesian Journal of Cardiology, 32(4), 221-2. https://doi.org/10.30701/ijc.v32i4.81
Issue
Vol. 32, No. 4 Oktober - Desember 2011
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