Of All Antioxidants, Would One Finally Be Used Clinically For Atherosclerotic Disease?
Abstract
Oxidation of LDL by oxygen free radicals results in unregulated uptake of modified LDL by macrophages in arterial wall. This is considered a key initiating factor for development and progression of atherosclerotic process. It is then logical to hypothesize that anti-oxidants, which can directly scavenge free radicals, can be useful in preventing atherosclerotic process. Initial support for this hypothesis accumulated rapidly from numerous in-vitro studies.Downloads
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References
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Jialal I, Devaraj S. Antioxidants and Atherosclerosis: Don’t Throw 3. Out the Baby With the bath water. Circulation. 2003;107:926-928
Diaz nm, Frei b, Vita ja, Keaney jf. Antioxidants and atherosclerotic heart disease. N eng J Med. 1997;107:410-416
Reddy KS. Diet and Cardiovascular Disease. In: Yusuf S, Cairn JA, Fallen EL, Gersh BJ, eds. Evidence-based Cardiology, 3rd ed. Singapore 2010: 111-124
Jialal I, Devaraj S. Antioxidants and Atherosclerosis: Don’t Throw 3. Out the Baby With the bath water. Circulation. 2003;107:926-928
Diaz nm, Frei b, Vita ja, Keaney jf. Antioxidants and atherosclerotic heart disease. N eng J Med. 1997;107:410-416
Published
2013-10-16
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Abstract views: 2682
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PDF downloads: 1819
How to Cite
Adiarto, S. (2013). Of All Antioxidants, Would One Finally Be Used Clinically For Atherosclerotic Disease?. Indonesian Journal of Cardiology, 34(1), 33-4. https://doi.org/10.30701/ijc.v34i1.303
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